Description

Pax-3 Protein CAS NO 138016-91-8 is a high-purity recombinant protein corresponding to the paired box protein Pax-3, a critical transcription factor involved in embryonic development and cellular differentiation. This product is essential for advanced life science research, enabling the study of gene regulation, myogenesis, and neural crest cell development. It is primarily utilized by researchers and developers in the fields of molecular biology, regenerative medicine, and oncology for applications such as protein-protein interaction studies, antibody production, and functional assays.

Application

• Biochemical Research: Used as a standard or reagent in studies investigating the role of Pax-3 in gene expression and cellular signaling pathways.
• Antibody Development & Validation: Serves as a critical antigen for the production, screening, and specificity testing of monoclonal and polyclonal antibodies.
• Diagnostic Assay Development: Employed in the research and development of diagnostic tools for conditions related to Pax-3 expression anomalies.
• Drug Discovery & Target Validation: Facilitates high-throughput screening and functional studies in pharmaceutical R&D targeting developmental disorders or cancers.
• Cell Culture & Differentiation Studies: Applied in in vitro models to study muscle and neural crest cell differentiation and regeneration.
• Protein Interaction Analysis: Used in techniques like co-immunoprecipitation (Co-IP) or pull-down assays to map protein interaction networks.

Basic Information

Product Name	Pax-3 Protein
CAS No.	138016-91-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Paired Box Protein Pax-3; PAX3 Protein; HuP2; WS1; CDHS; PAX3; Recombinant Human Pax-3 Protein; Pax-3 Transcription Factor; Paired Box Homeotic Gene 3 Protein
EINECS	Contact for details

Quality Control

Our Pax-3 Protein is manufactured under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including purity assessment by SDS-PAGE and HPLC, identity confirmation via mass spectrometry, and endotoxin level testing. A detailed Certificate of Analysis (COA) documenting identity, purity, concentration, and biological activity is provided with every shipment to support your research compliance and reproducibility requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Aliquot as recommended upon receipt to maintain optimal activity.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (Mass Spec)	Conforms
Purity (SDS-PAGE)	> 95%
Purity (HPLC)	> 98%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Determined by functional assay (e.g., EMSA)
Protein Concentration	As per COA
Buffer Composition	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.