Description

1-((4-((6-((2-Mercapto-2-Methylpropyl)Amino)-5-(((2-Mercapto-2-Methylpropyl)Amino)Methyl)Hexyl)Oxy)Benzoyl)Oxy)-2,5-Pyrrolidinedione Bis(Tetrafluoroborate(1-)) is a specialized, high-purity chemical intermediate featuring a unique bis-thiol and activated ester functionalization. This compound matters for its role as a critical building block in the synthesis of advanced materials and bioconjugates, offering precise reactivity for cross-linking and polymer modification. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, polymer science, and specialty chemical sectors for developing novel drug delivery systems, functional polymers, and high-performance adhesives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of targeted drug conjugates and prodrugs, particularly for antibody-drug conjugates (ADCs).
• Polymer Cross-Linking Agent: Used to introduce thiol-reactive sites and enhance the mechanical properties and stability of specialty polymers and hydrogels.
• Bioconjugation Reagent: Facilitates the site-specific labeling and modification of proteins, peptides, and other biomolecules for diagnostic and therapeutic applications.
• Surface Functionalization: Employed to modify material surfaces (e.g., gold, silica) to create bioactive or adhesive interfaces for sensors and medical devices.
• Research & Development: Serves as a valuable tool compound in organic and medicinal chemistry research for exploring new synthetic pathways.

Basic Information

Product Name	1-((4-((6-((2-Mercapto-2-Methylpropyl)Amino)-5-(((2-Mercapto-2-Methylpropyl)Amino)Methyl)Hexyl)Oxy)Benzoyl)Oxy)-2,5-Pyrrolidinedione Bis(Tetrafluoroborate(1-))
CAS No.	137932-18-4
Molecular Formula	C26H42B2F8N4O6S2
Molecular Weight	744.18 g/mol
Synonyms	N-Succinimidyl 4-((6-((2-Mercapto-2-methylpropyl)amino)-5-(((2-mercapto-2-methylpropyl)amino)methyl)hexyl)oxy)benzoate Bis(Tetrafluoroborate); Bis(2-mercapto-2-methylpropyl)amino-activated NHS ester tetrafluoroborate salt; Thiol-reactive NHS ester crosslinker; SATA-bis NHS ester tetrafluoroborate; N-Hydroxysuccinimide ester of a bis-thiol linker; 137932-18-4; CAS 137932-18-4
EINECS	Contact for details

Quality Control

Our 1-((4-((6-((2-Mercapto-2-Methylpropyl)Amino)-5-(((2-Mercapto-2-Methylpropyl)Amino)Methyl)Hexyl)Oxy)Benzoyl)Oxy)-2,5-Pyrrolidinedione Bis(Tetrafluoroborate(1-)) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets exacting research and process development standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and strictly light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use and protected from all light exposure. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.