Description

Htpx Heat Shock Protein CAS NO 137804-77-4 is a specialized recombinant protein belonging to the heat shock protein family, known for its critical role as a molecular chaperone in cellular stress response and protein homeostasis. This high-purity protein is essential for advanced research and development in life sciences, enabling the study of protein folding, aggregation, and cellular protection mechanisms. It is a key reagent for pharmaceutical discovery, biotechnology applications, and diagnostic assay development, serving researchers and process developers in demanding environments.

Application

• Biopharmaceutical Research & Development: Used as a critical tool in drug discovery for studying protein-protein interactions, target validation, and screening for chaperone-based therapeutics.
• Diagnostic Kit Manufacturing: Serves as a high-quality antigen or calibrator in the production of immunoassays and diagnostic tests for various diseases.
• Cell Culture & Bioprocessing: Employed to improve recombinant protein yield and stability in mammalian and bacterial expression systems by mitigating cellular stress.
• Biochemistry & Molecular Biology Studies: Essential for in vitro studies on protein folding, refolding, aggregation prevention, and understanding cellular stress pathways.
• Antibody Production: Acts as an immunogen for generating specific monoclonal or polyclonal antibodies for research and therapeutic use.
• Therapeutic Protein Formulation: Investigated for its potential as an excipient to stabilize other therapeutic proteins in final drug formulations.

Basic Information

Product Name	Htpx Heat Shock Protein
CAS No.	137804-77-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HSP; Heat Shock Protein Htpx; Recombinant Htpx; Molecular Chaperone Htpx; Stress-70 Protein; Chaperone Protein; Hsp70 family protein; Heat Shock 70kDa Protein; DnaK homolog; Endoplasmic reticulum chaperone BIP
EINECS	Contact for details

Quality Control

Our Htpx Heat Shock Protein is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including purity assessment by HPLC, identity confirmation via mass spectrometry and western blot, and rigorous endotoxin and bioburden testing to ensure it meets the exacting standards for research and in-vitro use. A detailed Certificate of Analysis (COA) documenting identity, purity, potency, and safety parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Avoid repeated freeze-thaw cycles. Aliquot upon receipt for single-use applications to maintain optimal activity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE & Western Blot)	Conforms
Purity (SDS-PAGE, reduced)	≥ 95%
Assay (Protein Content)	≥ 90% (BCA/Bradford)
Endotoxin	< 1.0 EU/µg
Bioburden	To USP <61> specifications
Solubility	Clear, colorless solution in specified buffer
Biological Activity (ATPase/Chaperone)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.