Description

(R)-2-Diphenyphosphino-2'-Ethyl-1,1'-Binaphthyl CAS NO 137769-32-5 is a high-value, chiral monophosphine ligand belonging to the Binaphthyl (BINAP) family. This compound matters because it is a critical catalyst component in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals with high selectivity and yield. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing and scaling up chiral catalytic processes.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Asymmetric C-C Bond Formation: Employed in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to construct chiral carbon frameworks.
• Pharmaceutical Manufacturing: Used in the synthesis of active pharmaceutical ingredients (APIs) requiring specific chirality, including cardiovascular, antiviral, and neurological drugs.
• Agrochemical Synthesis: Applied in the production of chiral herbicides, fungicides, and pesticides for enhanced efficacy and environmental safety.
• Fine Chemical Production: Facilitates the manufacture of enantiopure flavors, fragrances, and specialty chemicals.
• Academic & Industrial Research: A vital tool for developing new catalytic methodologies and exploring novel reaction pathways in organic chemistry.
• Catalyst Screening Libraries: Included in ligand libraries for high-throughput screening to identify optimal catalytic systems for specific transformations.

Basic Information

Product Name	(R)-2-Diphenyphosphino-2'-Ethyl-1,1'-Binaphthyl
CAS No.	137769-32-5
Molecular Formula	C34H27P
Molecular Weight	466.55 g/mol
Synonyms	(R)-2-(Diphenylphosphino)-2'-ethyl-1,1'-binaphthyl; (R)-2-Ethyl-2'-diphenylphosphino-1,1'-binaphthyl; (R)-Et-BINAP; (R)-2-Ethyl-BINAP; (R)-5,5',6,6',7,7',8,8'-Octahydro-2,2'-diethyl-1,1'-binaphthyl-2,2'-diyl)bis(diphenylphosphine) (related derivative); (R)-2-Ethyl-2'-(diphenylphosphino)-1,1'-binaphthyl; (R)-2'-Ethyl-2-diphenylphosphino-1,1'-binaphthyl
EINECS	Contact for details

Quality Control

Our (R)-2-Diphenyphosphino-2'-Ethyl-1,1'-Binaphthyl is produced under strict quality management protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot undergoes rigorous analytical testing, including chiral purity verification by HPLC. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized and moisture-sensitive; therefore, containers should be flushed with inert gas after each opening and stored in a cool, dry place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.