Description

(S)-(-)-2-(Diphenylphosphoryl)-2'-Ethyl-1,1'-Binaphthyl CAS NO 137769-29-0 is a chiral, axially-dissymmetric binaphthyl-based organophosphorus compound. This compound matters as a highly effective and selective ligand for asymmetric catalysis, enabling the synthesis of enantiomerically pure intermediates critical for advanced pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel synthetic routes and scaling up production of chiral active ingredients.

Application

• Asymmetric Hydrogenation: A key ligand for rhodium or ruthenium-catalyzed hydrogenation of prochiral olefins, ketones, and imines to produce chiral alcohols and amines.
• Pharmaceutical Intermediate Synthesis: Enables the enantioselective construction of complex molecular scaffolds for active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric C-C Bond Formation: Used in palladium-catalyzed cross-coupling reactions and other C-C bond-forming processes to install chiral centers with high enantiomeric excess.
• Agrochemical Synthesis: Facilitates the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.
• Fine Chemical Production: Applied in the synthesis of chiral flavors, fragrances, and advanced materials.

Basic Information

Product Name	(S)-(-)-2-(Diphenylphosphoryl)-2'-Ethyl-1,1'-Binaphthyl
CAS No.	137769-29-0
Molecular Formula	C34H27O1P
Molecular Weight	482.55 g/mol
Synonyms	(S)-(-)-2-(Diphenylphosphino)-2'-ethyl-1,1'-binaphthyl oxide; (S)-(-)-2-(Diphenylphosphinyl)-2'-ethyl-1,1'-binaphthyl; (S)-(-)-2-Ethyl-2'-(diphenylphosphoryl)-1,1'-binaphthyl; (S)-(-)-2-Ethyl-2'-(diphenylphosphinyl)-1,1'-binaphthyl; (S)-(-)-2-Ethyl-2'-(diphenylphosphino oxide)-1,1'-binaphthyl; (S)-(-)-2-Ethyl-2'-(diphenylphosphoryl)-1,1'-binaphthalene; (S)-(-)-2-Ethyl-2'-(diphenylphosphinyl)-1,1'-binaphthalene; (S)-(-)-2-Ethyl-2'-(diphenylphosphino oxide)-1,1'-binaphthalene
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-(Diphenylphosphoryl)-2'-Ethyl-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and NMR for structural confirmation, to ensure high chemical and optical purity suitable for demanding catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.