Description

Dna Strand Transfer Protein Alpha CAS NO 137750-51-7 is a specialized biochemical reagent, a protein involved in DNA recombination and repair processes. This compound is critical for advanced life science research, enabling the study of genetic stability, viral integration mechanisms, and targeted genome editing technologies. It is an essential tool for molecular biologists, biochemists, and pharmaceutical researchers working in academic institutions, biotechnology R&D, and drug discovery programs focused on oncology and genetic diseases.

Application

• Mechanistic Studies of Viral Integration: Used to investigate the role of strand transfer in retroviral life cycles, such as HIV.
• DNA Repair Pathway Research: Essential for in vitro assays studying homologous recombination and non-homologous end joining.
• Biochemical Assay Development: Serves as a key enzyme component in high-throughput screening platforms for drug discovery.
• Genome Editing Tool Validation: Used as a comparative control or component in studies involving CRISPR-Cas and other nuclease systems.
• Structural Biology: Provides protein material for X-ray crystallography and cryo-electron microscopy to determine 3D structures.
• Antiviral Drug Discovery: Acts as a target protein for screening and characterizing inhibitors of viral integrase enzymes.

Basic Information

Product Name	Dna Strand Transfer Protein Alpha
CAS No.	137750-51-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Strand Transferase Alpha; DNA Strand Transferase α; Recombinase Alpha Subunit; Integrase Cofactor Protein; HIV-1 Integrase Strand Transfer Inhibitor Target Protein; RAG-1 Like Protein; Transposase-like Protein; Site-specific Recombinase
EINECS	Contact for details

Quality Control

Our Dna Strand Transfer Protein Alpha is produced under stringent conditions suitable for research use. Each batch undergoes rigorous quality testing, including purity analysis and functional activity assays, to ensure consistency and performance in sensitive biochemical applications. Certificates of Analysis (COA) detailing purity, concentration, and specific activity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation. For short-term use, aliquoting is recommended to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (HPLC)	≥ 90%
Protein Concentration	≥ 1 mg/mL (after reconstitution)
Specific Activity	Defined units/mg (Batch-specific)
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in appropriate assay buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.