Description

Cycloheximide Sensitivity Factor CAS NO 137573-73-0 is a specialized biochemical reagent used to study cellular stress responses and protein synthesis inhibition pathways. This compound is critical for researchers investigating the mechanisms of action of cycloheximide and related translation inhibitors in eukaryotic systems. It serves as an essential tool for molecular biologists, pharmacologists, and toxicologists in academic, pharmaceutical, and biotechnology sectors for target validation and mechanistic studies.

Application

• Biochemical Research: Used as a key reagent to study the cellular sensitivity and resistance mechanisms to the protein synthesis inhibitor cycloheximide.
• Molecular Pharmacology: Employed in target identification and validation studies for novel antifungal and anti-proliferative agents.
• Signal Transduction Analysis: Facilitates the investigation of stress response pathways, including MAPK and JNK signaling cascades, in yeast and mammalian cell models.
• Toxicology Studies: Applied in cellular assays to understand the cytotoxic effects and selectivity of translation inhibitors.
• Drug Discovery Screening: Serves as a reference compound in high-throughput screening platforms to identify modulators of protein synthesis.
• Academic Laboratory Use: A standard research chemical for graduate-level and post-doctoral studies in cell biology and genetics.

Basic Information

Item	Detail
Product Name	Cycloheximide Sensitivity Factor
CAS No.	137573-73-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cycloheximide Sensitivity Protein; CSF; Cycloheximide Resistance Factor; Translation Inhibition Sensitivity Factor; CHX Sensitivity Factor; Eukaryotic Translation Inhibitor Sensitivity Factor; 137573-73-0; Cycloheximide-related Sensitivity Factor
EINECS	Contact for details

Quality Control

Our Cycloheximide Sensitivity Factor is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assessment by HPLC and identity confirmation. Certificates of Analysis (COA) documenting all relevant specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term stability, consider storage under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed in standard assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.