Description

4-Chloro-3-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to create novel active ingredients and functional organic intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a monomer or precursor for creating functional polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals and advanced intermediates.

Basic Information

Product Name	4-Chloro-3-Fluorobenzeneboronic Acid
CAS No.	137504-86-0
Molecular Formula	C6H5BClFO2
Molecular Weight	173.37 g/mol
Synonyms	(4-Chloro-3-fluorophenyl)boronic acid; 4-Chloro-3-fluorophenylboronic acid; 3-Fluoro-4-chlorobenzeneboronic acid; 3-Fluoro-4-chlorophenylboronic acid; B-(4-Chloro-3-fluorophenyl)boronic acid; 137504-86-0; 4-Chloro-3-fluoro-benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.