Description

3-Ethynyloxolan-3-Ol is a versatile heterocyclic building block featuring both an oxolane (tetrahydrofuran) ring and a reactive ethynyl group. This unique molecular structure makes it a valuable intermediate for synthesizing complex molecules in advanced research and development. It is particularly sought after by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients and by material scientists exploring new polymers and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic applications.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological processes via click chemistry or other bioorthogonal reactions.
• Fine Chemical Production: Acts as a building block for the synthesis of complex fragrances, flavors, and other high-value fine chemicals.

Basic Information

Product Name	3-Ethynyloxolan-3-Ol
CAS No.	137344-86-6
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	3-Ethynyloxolan-3-ol; 3-Ethynyltetrahydrofuran-3-ol; 3-Hydroxy-3-ethynyltetrahydrofuran; 3-Ethynyl-3-hydroxyoxolane; 3-Ethynyl-3-hydroxytetrahydrofuran; 3-Ethynyltetrahydro-3-furanol; Tetrahydro-3-ethynyl-3-furanol
EINECS	Contact for details

Quality Control

Our 3-Ethynyloxolan-3-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.