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Formyl-Methionyl-Delta(Z)-Dehydroleucyl-Phenylalanine Methyl Ester CAS NO 137320-56-0


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CAS No.:137320-56-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Formyl-Methionyl-Delta(Z)-Dehydroleucyl-Phenylalanine Methyl Ester is a synthetic peptide derivative of significant interest in advanced biochemical research and development. This compound serves as a critical building block and model substrate for studying enzyme mechanisms, particularly those involving formyl peptide receptors and peptide processing. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on immunology, inflammation pathways, and novel therapeutic agent discovery.

Application

  • Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly for formyl peptide receptor (FPR) research.
  • Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and screening of novel anti-inflammatory or immunomodulatory drug candidates.
  • Cell Signaling Studies: Employed in vitro to investigate neutrophil chemotaxis, phagocytosis, and other immune cell activation pathways mediated by formylated peptides.
  • Protease & Peptidase Assays: Acts as a model compound to study the specificity and kinetics of various proteolytic enzymes.
  • Academic Research: Provides a tool for graduate and post-doctoral level research in biochemistry, molecular biology, and medicinal chemistry departments.
  • Reference Standard: Used for analytical method development, calibration, and quality control in peptide analysis via HPLC and LC-MS.

Basic Information

Product Name Formyl-Methionyl-Delta(Z)-Dehydroleucyl-Phenylalanine Methyl Ester
CAS No. 137320-56-0
Molecular Formula C28H40N4O7S
Molecular Weight 576.71 g/mol
Synonyms fMLF-OMe; N-Formyl-Met-Leu-Phe-OMe (dehydro variant); Formyl-Met-δZ-DehydroLeu-Phe-OMe; For-Met-δZ-DhLeu-Phe-OCH3; N-Formylmethionyl-dehydroleucyl-phenylalanine methyl ester; Chemotactic Peptide Analog; fMLF Methyl Ester Analog; Formyl Peptide Receptor Ligand
EINECS Contact for details

Quality Control

Our Formyl-Methionyl-Delta(Z)-Dehydroleucyl-Phenylalanine Methyl Ester is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized by advanced analytical techniques including HPLC, MS, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and analytical data is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms
Identification (MS) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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