Description

n-[(1S,2S)-2-Hydroxycyclopentyl]Acetamide is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its defined stereochemistry, which is critical for the development of enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture dictates biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Serves as a versatile precursor for constructing complex molecules with defined stereocenters via further functionalization of the hydroxy and amide groups.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereoisomers often exhibit superior efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed as a scaffold for creating chiral ligands and organocatalysts used in asymmetric transformations.
• Fine Chemical Production: Integral to the manufacture of specialty chemicals requiring high stereochemical purity for advanced material science applications.
• Academic & R&D: A valuable compound for methodological research in organic chemistry and medicinal chemistry programs at universities and corporate R&D centers.

Basic Information

Product Name	n-[(1S,2S)-2-Hydroxycyclopentyl]Acetamide
CAS No.	137254-02-5
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(1S,2S)-2-Acetamidocyclopentanol; (1S,2S)-2-(Acetylamino)cyclopentanol; Acetamide, N-[(1S,2S)-2-hydroxycyclopentyl]-; (1S,2S)-N-(2-Hydroxycyclopentyl)acetamide; (1S,2S)-2-Hydroxy-N-acetylcyclopentylamine; cis-2-Acetamidocyclopentanol; Chiral Cyclopentyl Acetamide Derivative
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-Hydroxycyclopentyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.