Description

(R)-Dm-Binap is a high-value, chiral diphosphine ligand widely recognized for its exceptional enantioselectivity in asymmetric catalysis. This compound is critical for enabling the synthesis of single-enantiomer intermediates and active pharmaceutical ingredients (APIs) with high optical purity. It is an indispensable tool for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop efficient and sustainable synthetic routes.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective hydrogenation of dehydroamino acids, enamides, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Key catalyst component in the production of chiral drugs for cardiovascular, central nervous system, and metabolic diseases.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Facilitates asymmetric C-C bond-forming reactions, including cross-coupling and allylic alkylation.
• Academic & Industrial R&D: A standard ligand in method development for new catalytic transformations in both academic laboratories and industrial pilot plants.
• Catalyst Library Development: Serves as a benchmark compound for screening and optimizing new chiral catalyst systems.

Basic Information

Product Name	(R)-Dm-Binap
CAS No.	137219-86-4
Molecular Formula	C32H24P2
Molecular Weight	478.48 g/mol
Synonyms	(R)-2,2'-Bis(di(3,5-xylyl)phosphino)-1,1'-binaphthyl; (R)-2,2'-Bis[bis(3,5-dimethylphenyl)phosphino]-1,1'-binaphthyl; (R)-DM-BINAP; (R)-Bis(3,5-dimethylphenylphosphino)-1,1'-binaphthyl; (R)-4,4',6,6'-Tetramethyl-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl; (R)-XYLYL-BINAP
EINECS	Contact for details

Quality Control

Our (R)-Dm-Binap is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC, 31P NMR, and 1H NMR, to ensure high chemical and optical purity. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.