Description

Parathyroid Hormone (3-84), Formylmethionyl- is a synthetic peptide fragment of the parathyroid hormone (PTH), specifically the N-terminal formylmethionyl derivative of the 3-84 sequence. This compound is a critical research tool for studying PTH receptor interactions, calcium homeostasis, and bone metabolism pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on endocrine disorders, osteoporosis research, and peptide-based therapeutic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies of parathyroid hormone function, receptor binding assays, and signal transduction mechanisms.
• Drug Discovery & Development: Serves as a key intermediate or pharmacological tool in the screening and development of novel therapeutics for hyperparathyroidism, hypoparathyroidism, and metabolic bone diseases.
• In Vitro Diagnostics (IVD): Employed in the development and calibration of immunoassays and diagnostic kits designed to measure PTH levels or related biomarkers.
• Cell Biology Studies: Applied in cell culture experiments to investigate the effects of PTH fragments on osteoblast and osteoclast activity, renal calcium handling, and cellular differentiation.
• Peptide Chemistry & Biochemistry: Acts as a substrate or model compound for studying peptide stability, modification techniques, and structure-activity relationships (SAR).

Basic Information

Product Name	Parathyroid Hormone (3-84), Formylmethionyl-
CAS No.	137085-29-1
Molecular Formula	C433H702N124O126S2
Molecular Weight	~9427.6 g/mol
Synonyms	Formylmethionyl-PTH (3-84); fMet-PTH (3-84); N-Formylmethionyl Parathyroid Hormone (3-84); PTH (3-84), N-formylmethionyl-; Parathyroid Hormone Fragment (3-84), Formylmethionyl derivative; fM-PTH(3-84); CAS 137085-29-1
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone (3-84), Formylmethionyl- is produced under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and impurity profiles. We adhere to stringent internal quality standards to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.