Description

3-[(Trifluoroacetyl)Amino]Benzamide is a high-purity, specialized organic intermediate featuring a reactive trifluoroacetyl-amino group. This compound is critical for the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique fluorine-containing moiety imparts desirable metabolic stability and bioavailability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Chemical Research & Development: Serves as a versatile precursor for introducing the trifluoroacetamide functional group into more complex molecules during exploratory chemistry.
• Material Science: Potential monomer or additive in the development of specialty polymers with enhanced chemical resistance and thermal stability.
• Ligand Synthesis: Can be utilized for creating novel ligands for catalysis or metal-organic frameworks (MOFs) in academic and industrial research.

Basic Information

Product Name	3-[(Trifluoroacetyl)Amino]Benzamide
CAS No.	137084-97-0
Molecular Formula	C9H7F3N2O2
Molecular Weight	232.16 g/mol
Synonyms	3-(Trifluoroacetamido)benzamide; N-(3-Carbamoylphenyl)-2,2,2-trifluoroacetamide; 3-Aminobenzamide Trifluoroacetate Derivative; 3-Trifluoroacetylamino Benzamide; 2,2,2-Trifluoro-N-(3-carbamoylphenyl)acetamide; Benzamide, 3-[(trifluoroacetyl)amino]-; 137084-97-0; TFAB
EINECS	Contact for details

Quality Control

Our 3-[(Trifluoroacetyl)Amino]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.