Description

1,4-Diethynyl-2-Fluorobenzene is a high-value, multi-functional aromatic building block characterized by its two terminal alkyne groups and fluorine substituent. This unique structure makes it a critical intermediate for synthesizing advanced materials and complex organic molecules. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key synthon for constructing complex drug candidates, particularly in kinase inhibitor and oncology research.
• Agrochemical Synthesis: Used in the development of novel active ingredients with enhanced efficacy and environmental profiles.
• Material Science & Polymer Chemistry: A fundamental monomer for creating conjugated polymers, dendrimers, and other advanced materials for organic electronics (e.g., OLEDs, OFETs).
• Cross-Coupling Reactions: An excellent substrate for Sonogashira, Glaser, and other palladium-catalyzed coupling reactions to build extended π-systems.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and molecular recognition.
• Fluorine Chemistry Research: Provides a platform for studying the effects of fluorine substitution on reactivity and material properties.

Basic Information

Product Name	1,4-Diethynyl-2-Fluorobenzene
CAS No.	137000-66-9
Molecular Formula	C10H5F
Molecular Weight	144.15 g/mol
Synonyms	2-Fluoro-1,4-diethynylbenzene; 1,4-Bis(ethynyl)-2-fluorobenzene; 2-Fluoro-p-diethynylbenzene; 2-Fluorobenzene-1,4-diyldiethyne; 1,4-Diethynyl-2-fluoro-benzene; p-Diethynyl-2-fluorobenzene
EINECS	Contact for details

Quality Control

Our 1,4-Diethynyl-2-Fluorobenzene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and production. We provide comprehensive analytical data including HPLC purity, NMR, and GC-MS characterization. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, minimize exposure to air and light during handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.