Description

2-Fluoro-6-Nitrophenylacetic Acid is a versatile fluorinated aromatic building block characterized by its acetic acid and nitro substituents. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced materials, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals with unique electronic and optical properties.
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Fluoro-6-Nitrophenylacetic Acid
CAS No.	136916-19-3
Molecular Formula	C8H6FNO4
Molecular Weight	199.14 g/mol
Synonyms	(2-Fluoro-6-nitrophenyl)acetic acid; 2-(2-Fluoro-6-nitrophenyl)acetic acid; α-(2-Fluoro-6-nitrophenyl)acetic acid; NSC 405124; 2-Fluoro-6-nitrobenzeneacetic acid; 6-Nitro-2-fluorophenylacetic acid; o-Fluoro-o'-nitrophenylacetic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Nitrophenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support cGMP and ISO 9001 standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.