Description

Saliva-Binding Protein, Streptococcus Sanguis 12 is a specialized bacterial protein derived from the oral commensal *Streptococcus sanguinis*. This compound is of significant interest in biochemical and microbiological research for its role in bacterial adhesion and biofilm formation within the oral cavity. It serves as a critical reagent for researchers and developers in the fields of dental health, microbiology, and the development of anti-adhesion therapies. Its study is essential for understanding the mechanisms of oral colonization and for the design of novel preventive strategies against dental plaque and related conditions.

Application

• Dental Research: Fundamental studies on the mechanisms of bacterial adhesion to tooth surfaces and salivary pellicle.
• Biofilm Investigation: Used as a model protein to study the initial stages of oral biofilm (plaque) formation and development.
• Diagnostic Development: Potential use in the development of diagnostic assays to detect specific bacterial interactions or host immune responses.
• Therapeutic Target Research: Serves as a target molecule for screening and evaluating novel anti-adhesion compounds, mouthwashes, or dental materials.
• Oral Microbiology Studies: Essential for in vitro studies exploring the competitive and cooperative interactions between different oral bacterial species.
• Biomaterial Coating Studies: Research on protein-surface interactions relevant to the biocompatibility of dental implants and prosthetics.

Basic Information

Product Name	Saliva-Binding Protein, Streptococcus Sanguis 12
CAS No.	136806-48-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SspB (Streptococcus sanguis antigen B); Salivary receptor-binding protein; S. sanguinis adhesion protein; Antigen B; Oral streptococcal adhesion protein; Plaque formation protein; Bacterial salivary agglutinin receptor
EINECS	Contact for details

Quality Control

Our Saliva-Binding Protein, Streptococcus Sanguis 12 is produced and handled under controlled conditions to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, which may include purity assessment via electrophoresis (SDS-PAGE) and functional activity assays. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific activity is provided with every shipment to support your research integrity and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot into working portions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE)	Corresponds to reference standard
Purity (SDS-PAGE)	≥ 90%
Protein Content (BCA)	≥ 90% of dry weight
Biological Activity	Contact for details
Endotoxin Level (LAL)	< 1.0 EU/µg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.