Description

(+)-1,2-Bis[(2R,5R)-2,5-Diisopropylphospholano]Benzene CAS NO 136705-65-2 is a high-value, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its core value lies in enabling highly enantioselective transformations, particularly in hydrogenation reactions, which are critical for producing single-enantiomer pharmaceuticals and fine chemicals. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemical control.

Application

• Asymmetric Hydrogenation Catalyst Ligand: A key component for rhodium and ruthenium complexes used in the enantioselective hydrogenation of olefins, ketones, and imines.
• Pharmaceutical Intermediate Synthesis: Critical for the production of chiral active pharmaceutical ingredients (APIs), including β-amino acids and other complex molecules.
• Agrochemical Manufacturing: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Enables the synthesis of specialty chemicals, flavors, and fragrances with high optical purity.
• Academic and Industrial R&D: Serves as a benchmark ligand in methodological development for new catalytic asymmetric processes.
• Material Science: Potential applications in the development of chiral polymers and advanced functional materials.

Basic Information

Product Name	(+)-1,2-Bis[(2R,5R)-2,5-Diisopropylphospholano]Benzene
CAS No.	136705-65-2
Molecular Formula	C26H44P2
Molecular Weight	418.57 g/mol
Synonyms	(R,R)-DIPAMP; (R,R)-1,2-Bis[(2,5-diisopropylphospholano)]benzene; (2R,2'R,5R,5'R)-1,1'-(1,2-Phenylene)bis(2,5-diisopropylphospholane); (+)-DIPAMP; (R,R)-DIPAMP ligand; DIPAMP; 1,2-Bis[(2R,5R)-2,5-diisopropylphospholanyl]benzene
EINECS	Contact for details

Quality Control

Our (+)-1,2-Bis[(2R,5R)-2,5-Diisopropylphospholano]Benzene is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity, which is critical for catalytic performance. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, enantiomeric excess, and impurity profile. We support compliance with cGMP and ISO 9001 standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.