Description

(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene is a high-purity, chiral bisphosphine ligand of significant importance in asymmetric catalysis. Its precise stereochemistry makes it a critical component for creating highly selective catalytic systems, enabling the production of enantiomerically pure compounds. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require advanced tools for asymmetric hydrogenation and other transition metal-catalyzed reactions.

Application

• As a privileged ligand in asymmetric hydrogenation reactions for the synthesis of chiral pharmaceutical intermediates.
• Catalyst component for the enantioselective synthesis of amino acids, amines, and other bioactive molecules.
• Used in the development of novel catalytic systems for academic and industrial R&D in organic synthesis.
• Key reagent for the production of high-value fine chemicals and specialty materials requiring precise stereocontrol.
• Employed in process chemistry for scaling up enantioselective transformations.

Basic Information

Product Name	(-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene
CAS No.	136705-64-1
Molecular Formula	C26H44P2
Molecular Weight	418.58 g/mol
Synonyms	(-)-1,2-Bis((2R,5R)-2,5-diethylphospholano)benzene; (R,R)-(-)-1,2-Bis(2,5-diethylphospholano)benzene; (R,R)-DIPAMP derivative; Et-DuPhos; 1,2-Bis((2R,5R)-2,5-diethylphospholanyl)benzene; Chiral bisphospholane ligand; Asymmetric hydrogenation ligand; CAS 136705-64-1
EINECS	Contact for details

Quality Control

Our (-)-1,2-Bis((2R,5R)-2,5-Diethylphospholano)Benzene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and identity is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, the container should only be opened in an inert environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.