Description

Cyclopropane, 1-(1,1-Dimethylethoxy)-2-Ethynyl-, cis- (9Ci) is a specialized cis-substituted cyclopropane derivative featuring both an ethynyl and a tert-butoxy functional group. This unique molecular architecture makes it a valuable advanced synthetic intermediate for constructing complex organic frameworks, particularly in medicinal chemistry and materials science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those requiring rigid, three-dimensional cyclopropane scaffolds.
• Agrochemical Research: Used in developing new active ingredients for crop protection with potentially enhanced biological activity and stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers and specialty materials.
• Organic Synthesis Reagent: Employed in cycloaddition reactions and other transformations to introduce the cis-cyclopropyl moiety into target molecules.
• Ligand and Catalyst Development: Utilized for creating novel chiral ligands or organometallic complexes due to its stereodefined structure and functional handles.
• Academic and Industrial R&D: Fundamental research tool for exploring new chemical spaces and reaction methodologies in synthetic chemistry.

Basic Information

Product Name	Cyclopropane, 1-(1,1-Dimethylethoxy)-2-Ethynyl-, cis- (9Ci)
CAS No.	136689-61-7
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	cis-1-(tert-Butoxy)-2-ethynylcyclopropane; 1-(tert-Butoxy)-2-ethynylcyclopropane, cis-; 1-(1,1-Dimethylethoxy)-2-ethynylcyclopropane, cis-; cis-1-tert-Butoxy-2-ethynylcyclopropane; 2-Ethynyl-1-(1,1-dimethylethoxy)cyclopropane, cis-; (cis)-1-(tert-Butoxy)-2-ethynylcyclopropane; 136689-61-7
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure the consistency and purity of our advanced intermediates. Each batch of Cyclopropane, 1-(1,1-Dimethylethoxy)-2-Ethynyl-, cis- (9Ci) is analyzed using modern analytical techniques including GC, HPLC, and NMR to verify identity, purity, and isomeric composition. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate to maintain stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
cis-Isomer Content	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.