Description

Boc-Arg(Mts)-Oh CAS NO 136625-03-1 is a protected derivative of the amino acid L-arginine, featuring Boc (tert-butoxycarbonyl) and Mts (mesitylenesulfonyl) protecting groups. This compound is a critical building block in solid-phase peptide synthesis (SPPS), enabling the controlled and sequential assembly of complex peptides and proteins. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors who require high-purity, protected amino acids for the development of novel therapeutics, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc/t-Bu strategy, used in the automated synthesis of peptides for research and pharmaceutical development.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the synthesis of peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation and Labeling: Used to incorporate arginine residues into peptides designed for bioconjugation with dyes, tags, or other functional molecules.
• Biochemical Research: Employed in academic and industrial research laboratories for studying protein-protein interactions, enzyme substrates, and signal transduction pathways.
• Production of Bioactive Peptides: Essential for manufacturing peptides with therapeutic potential, such as antimicrobial peptides, hormone analogs, and cell-penetrating peptides.
• Combinatorial Chemistry Libraries: Used as a building block to create diverse libraries of peptide compounds for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	Boc-Arg(Mts)-Oh
CAS No.	136625-03-1
Molecular Formula	C20H32N4O6S
Molecular Weight	456.56 g/mol
Synonyms	Nα-Boc-Nω-Mts-L-arginine; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-guanidinopentanoic acid (common misnomer for related compound); Boc-L-arginine(Mts)-OH; tert-Butyloxycarbonyl-L-arginine(mesitylsulfonyl)-OH; Nα-tert-Butoxycarbonyl-Nω-mesitylenesulfonyl-L-arginine; Fmoc-Arg(Mts)-OH (related Fmoc-protected version); Protected L-Arginine derivative; Boc-Arg(Mts)
EINECS	Contact for details

Quality Control

Our Boc-Arg(Mts)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurities is provided with every shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.