Description

Bicyclo[2.2.1]Heptane-2-Carboxamide, n-Hydroxy- (9Ci) is a specialized organic compound featuring a norbornane (bicyclo[2.2.1]heptane) skeleton functionalized with a hydroxamic acid group. This unique structure, CAS NO 136561-38-1, makes it a valuable intermediate and building block in advanced organic synthesis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with specific stereochemistry and biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting enzymes like metalloproteases or histone deacetylases (HDACs) where the hydroxamic acid moiety acts as a potent zinc-binding group.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the rigid norbornane structure for enhanced stability and bioactivity.
• Chemical Biology Probe: Serves as a core structure for creating activity-based probes and inhibitors to study enzyme function and mechanism in biochemical pathways.
• Material Science Precursor: Potential monomer or cross-linking agent for synthesizing polymers with unique thermal and mechanical properties derived from the strained bicyclic system.
• Catalyst Ligand Synthesis: Intermediate for preparing chiral ligands used in asymmetric catalysis, benefiting from the well-defined three-dimensional geometry of the norbornane framework.
• Academic & Institutional Research: Fundamental compound for methodological studies in organic synthesis, including cycloaddition reactions and stereoselective functionalization.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxamide, n-Hydroxy- (9Ci)
CAS No.	136561-38-1
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	N-Hydroxybicyclo[2.2.1]heptane-2-carboxamide; 2-Norbornanecarbohydroxamic Acid; N-Hydroxynorbornane-2-carboxamide; endo-N-Hydroxybicyclo[2.2.1]heptane-2-carboxamide; exo-N-Hydroxybicyclo[2.2.1]heptane-2-carboxamide; Bicyclo[2.2.1]heptane-2-carbohydroxamic acid; Norbornane hydroxamic acid
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.1]Heptane-2-Carboxamide, n-Hydroxy- (9Ci) is subjected to rigorous analytical testing to ensure identity, purity, and consistency. Our quality protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods (IR, NMR), and specific impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.