Description

(S)-2-Hydroxy-2-(5-Methylfuryl)Acetonitrile is a high-value chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its core value lies in the enantioselective construction of complex molecules, offering a pathway to high-purity, single-isomer products critical for efficacy and safety. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active pharmaceutical ingredients (APIs), chiral ligands, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereochemical purity.
• Agrochemical Synthesis: Used in the research and development of enantiomerically pure pesticides and herbicides, where the specific (S)-configuration can be crucial for biological activity.
• Fine Chemical Production: Serves as a versatile building block for creating complex, value-added molecules in custom synthesis and process development.
• Chiral Ligand & Catalyst Development: Employed as a precursor or core structure in the design of asymmetric catalysts and auxiliaries for enantioselective transformations.
• Academic & Industrial Research: A valuable tool for methodological studies in organic chemistry, enabling the exploration of new synthetic routes and reaction mechanisms.

Basic Information

Product Name	(S)-2-Hydroxy-2-(5-Methylfuryl)Acetonitrile
CAS No.	136521-57-8
Molecular Formula	C8H7NO2
Molecular Weight	149.15 g/mol
Synonyms	(S)-2-Hydroxy-2-(5-methyl-2-furyl)acetonitrile; (S)-2-(5-Methylfuran-2-yl)-2-hydroxyacetonitrile; (S)-α-Hydroxy-5-methyl-2-furanacetonitrile; (S)-5-Methyl-2-furylglycolonitrile; (S)-2-(5-Methyl-2-furyl)-2-hydroxyacetonitrile; (S)-2-Hydroxy-2-(5-methylfuran-2-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our (S)-2-Hydroxy-2-(5-Methylfuryl)Acetonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes rigorous analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR spectroscopy, and quantification of key impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.