Description

Benzene, 1-Bromo-4-[1-(Trifluoromethyl)ethenyl]- is a specialized aromatic building block featuring both bromine and a trifluoromethyl-substituted alkene functional group. This unique structure makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where fluorine substitution is critical for modulating properties like metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those requiring fluorinated aromatic or heteroaromatic scaffolds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to introduce fluorine into polymers, improving chemical resistance and surface properties.
• Organic Synthesis Building Block: Utilized in Suzuki, Heck, and other cross-coupling reactions due to the reactive bromine substituent, enabling further functionalization.
• Fluorinated Surfactant & Coating Precursor: Acts as an intermediate for creating surface-active agents and specialty coatings with low surface energy.

Basic Information

Product Name	Benzene, 1-Bromo-4-[1-(Trifluoromethyl)ethenyl]-
CAS No.	136476-20-5
Molecular Formula	C9H6BrF3
Molecular Weight	251.05 g/mol
Synonyms	1-Bromo-4-(1-trifluoromethylvinyl)benzene; 4-Bromo-α-(trifluoromethyl)styrene; p-Bromo-α-(trifluoromethyl)styrene; 1-Bromo-4-[1-(trifluoromethyl)vinyl]benzene; (4-Bromophenyl)(trifluoromethyl)ethylene; 4-Bromo-α,α,α-trifluoromethylstyrene; [4-Bromophenyl](trifluoromethyl)ethene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-Bromo-4-[1-(Trifluoromethyl)ethenyl]- adheres to stringent in-process controls and final batch analysis to ensure consistent purity and performance. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We operate under a quality management system and can supply material to meet specific customer requirements for research, development, and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.5 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.