Description

Fibronectin Cs-1 Fragment (1978-1985) is a specific, bioactive peptide sequence derived from the cell-binding domain of human fibronectin. This fragment is critical for research and development in cell adhesion and signaling studies, offering a defined tool to investigate integrin-mediated processes. It is primarily utilized by biotechnology, pharmaceutical, and academic research sectors focusing on wound healing, tissue engineering, and cancer metastasis.

Application

• Cell Adhesion & Migration Studies: Used as a defined substrate to study the mechanisms of cell attachment, spreading, and motility in vitro.
• Integrin-Specific Research: Serves as a selective ligand for α5β1 and αvβ3 integrins in receptor-ligand interaction assays.
• Biomaterial & Tissue Engineering: Coated onto surfaces to enhance the biocompatibility and cellular integration of synthetic scaffolds and implants.
• Wound Healing Models: Applied in research models to understand and promote re-epithelialization and tissue repair.
• Cancer Research: Investigated for its role in tumor cell adhesion, angiogenesis, and metastatic progression.
• High-Throughput Screening (HTS): Employed in drug discovery platforms to identify compounds that modulate integrin-mediated pathways.

Basic Information

Product Name	Fibronectin Cs-1 Fragment (1978-1985)
CAS No.	136466-51-8
Molecular Formula	C38H62N12O11
Molecular Weight	862.98 g/mol
Synonyms	CS1 Peptide; Fibronectin CS1 Peptide; CS-1 Fragment; Arg-Gly-Asp-Ser (RGDS) containing peptide; FN CS1; Cell-binding fibronectin peptide; LDV peptide; Connecting Segment-1 peptide; (1978)DELPQLVTLPHPNLHGPEILDVPST(1985); Human Fibronectin Fragment
EINECS	Contact for details

Quality Control

Our Fibronectin Cs-1 Fragment is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Quality is verified through comprehensive analytical methods including HPLC for purity and MS for sequence confirmation. A Certificate of Analysis (COA) detailing purity, endotoxin levels, and biological activity is provided with each batch to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Peptide Content	≥ 80%
Endotoxin Level	< 1.0 EU/mg
Solubility	Soluble in water or PBS, pH 7.2-7.4

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.