Description

n-(tert-Butyl)Decahydroisoquinoline-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex decahydroisoquinoline scaffold. This compound matters for its critical role in the synthesis of sophisticated active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in innovative drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel therapeutic agents, especially for central nervous system (CNS) and cardiovascular drug candidates.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex nitrogen-containing heterocycles and studying structure-activity relationships (SAR).
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Reference Standard: High-purity material for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Tool Compound: Potential use in pharmacological studies as a ligand or probe for investigating specific biological targets and pathways.

Basic Information

Product Name	n-(tert-Butyl)Decahydroisoquinoline-3-Carboxamide
CAS No.	136465-81-1
Molecular Formula	C₁₄H₂₆N₂O
Molecular Weight	238.37 g/mol
Synonyms	1,2,3,4,4a,5,6,7,8,8a-Decahydro-N-(1,1-dimethylethyl)-3-isoquinolinecarboxamide; 3-[(tert-Butylcarbamoyl)]decahydroisoquinoline; tert-Butyl Decahydroisoquinoline-3-Carboxamide; N-(tert-Butyl)-1,2,3,4,4a,5,6,7,8,8a-decahydroisoquinoline-3-carboxamide; Decahydro-N-(tert-butyl)isoquinoline-3-carboxamide; TB-DHIQ-Carboxamide
EINECS	Contact for details

Quality Control

Our n-(tert-Butyl)Decahydroisoquinoline-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.