Description

(R,R'')-2,2''-Bis(Diphenylphosphino)-1,1''-Biferrocene is a high-value, chiral bidentate phosphine ligand featuring a unique planar chiral ferrocenyl backbone. This compound matters as a sophisticated catalyst component, enabling highly enantioselective transformations critical for producing single-isomer pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for asymmetric hydrogenation, cross-coupling, and other transition metal-catalyzed reactions.

Application

• Asymmetric Hydrogenation Catalyst Ligand: For the enantioselective reduction of prochiral olefins, ketones, and imines in pharmaceutical intermediate synthesis.
• Cross-Coupling Reactions: As a ligand in palladium-catalyzed Suzuki, Heck, and Negishi couplings for constructing complex biaryl and C-C bonds.
• Asymmetric Allylic Substitution: Enables the creation of chiral centers with high enantiomeric excess in allylic alkylation and amination reactions.
• Hydrosilylation Catalyst Component: Used in the production of chiral silanes and enantioselective reduction processes.
• Academic & Industrial R&D: A key tool for developing novel catalytic methodologies and exploring new reaction pathways.
• Fine Chemical Synthesis: For the production of specialty chemicals, flavors, fragrances, and advanced materials requiring precise stereochemical control.

Basic Information

Item	Detail
Product Name	(R,R'')-2,2''-Bis(Diphenylphosphino)-1,1''-Biferrocene
CAS No.	136274-57-2
Molecular Formula	C46H36Fe2P2
Molecular Weight	762.42 g/mol
Synonyms	(R,R)-BIFEP; (R,R)-2,2'-Bis(diphenylphosphino)-1,1'-biferrocene; (R,R)-1,1'-Biferrocenediyl-bis(diphenylphosphine); (R,R)-Bis(diphenylphosphino)biferrocene; (R,R)-BPPF; (R,R)-Biferrocenylbis(diphenylphosphine); (R,R)-DPBFe; (R,R)-JOSIPHOS analog
EINECS	Contact for details

Quality Control

Every batch of (R,R'')-2,2''-Bis(Diphenylphosphino)-1,1''-Biferrocene is produced and handled under strict inert atmosphere conditions to prevent oxidation. Our products undergo rigorous quality testing, including chiral HPLC and NMR analysis, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided with each shipment to ensure compliance with your research and process development requirements.

Storage

Preserve in a tightly closed container under an inert atmosphere (argon or nitrogen), protected from light. Store at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air or light will degrade its catalytic performance.

Specification

Item	Specification
Appearance	Orange to red crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.