Description

1-Butoxy-2,3-Difluorobenzene is a high-purity fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both alkoxy and fluorine substituents, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorobenzene moiety contributes to biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce the butoxy-difluorophenyl group into target molecules.
• Chemical Research & Development: A valuable scaffold for discovering new compounds with potential biological or material science applications in academic and industrial labs.

Basic Information

Product Name	1-Butoxy-2,3-Difluorobenzene
CAS No.	136239-66-2
Molecular Formula	C₁₀H₁₂F₂O
Molecular Weight	186.20 g/mol
Synonyms	2,3-Difluorophenyl butyl ether; Butyl 2,3-difluorophenyl ether; 1-Butoxy-2,3-difluorobenzene; 2,3-Difluoro-1-butoxybenzene; o,m-Difluorophenyl butyl ether; 2,3-DFB; 2,3-Difluorophenetole (butyl analog)
EINECS	Contact for details

Quality Control

Our 1-Butoxy-2,3-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.