Description

Snf2 Protein CAS NO 136219-48-2 is a high-purity, biologically active protein essential for chromatin remodeling and transcriptional regulation. This product is critical for researchers and developers requiring a reliable and consistent reagent for advanced molecular biology and epigenetics studies. It is primarily utilized in life science research, pharmaceutical development, and diagnostic assay manufacturing where precise control of gene expression mechanisms is paramount.

Application

• Chromatin Remodeling Studies: Used as a core component in in vitro assays to investigate ATP-dependent nucleosome sliding and histone displacement.
• Transcriptional Regulation Research: Essential for studying the mechanisms of gene activation and repression in eukaryotic systems.
• Enzymatic Activity Assays: Serves as a standard or active enzyme in functional assays to screen for modulators or inhibitors.
• Protein-Protein Interaction Analysis: Employed in pull-down, co-immunoprecipitation (Co-IP), and surface plasmon resonance (SPR) experiments to map interaction networks.
• Biopharmaceutical Development: Used in target validation and high-throughput screening (HTS) campaigns for drug discovery focused on epigenetic targets.
• Diagnostic Kit Manufacturing: Incorporated as a key reagent in specialized diagnostic kits for research into chromatin-related disorders.

Basic Information

Product Name	Snf2 Protein
CAS No.	136219-48-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	SNF2; SNF2 homolog; Sucrose Non-Fermenting Protein 2; Chromatin Remodeling Factor SNF2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2; ATP-dependent helicase SNF2; Global transcription activator SNF2L4; SMARCA2 (Gene name-derived); Yeast SNF2 homolog
EINECS	Contact for details

Quality Control

Our Snf2 Protein is produced and tested under stringent quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and functional activity, meeting the exacting standards required for research and development. A detailed Certificate of Analysis (COA) documenting purity (by SDS-PAGE and HPLC), endotoxin levels, and specific activity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at ≤ -20°C in aliquots to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use. Handle under appropriate laboratory conditions.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Identification (SDS-PAGE)	Single major band at expected molecular weight
Purity (HPLC)	≥ 90%
Protein Concentration	As per COA (e.g., 1 mg/mL)
Specific Activity	Defined units/mg (ATPase or remodeling assay)
Endotoxin Level	< 1.0 EU/μg
Buffer Composition	Specified on COA (e.g., Tris-HCl, Glycerol, DTT)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.