Description

4-Fluoro-7-Hydroxy-1-Indanone is a high-purity fluorinated indanone derivative, serving as a critical advanced pharmaceutical intermediate. Its unique molecular structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a versatile building block for synthesizing complex bioactive molecules. This compound is essential for research and development in pharmaceutical chemistry, particularly for medicinal chemists and process development scientists working on novel drug candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or precursor in drug discovery programs for structure-activity relationship (SAR) studies.
• Fluorinated Compound Synthesis: Serves as a starting material for introducing the fluorinated indanone moiety into larger molecular architectures to modulate pharmacokinetic properties.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Utilized in academic and industrial R&D for constructing heterocyclic compounds and other specialty chemicals.

Basic Information

Product Name	4-Fluoro-7-Hydroxy-1-Indanone
CAS No.	136191-16-7
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	7-Hydroxy-4-fluoroindan-1-one; 4-Fluoro-7-hydroxy-2,3-dihydro-1H-inden-1-one; 1-Indanone, 4-fluoro-7-hydroxy-; 4-Fluoro-7-hydroxyindan-1-one; 136191-16-7
EINECS	Contact for details

Quality Control

Our 4-Fluoro-7-Hydroxy-1-Indanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to prevent degradation from moisture and light exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.