Description

Alpaha-Cyano-β-Hydroxy-n-(4-(Trifluoromethyl)Phenyl)-3-(4-(Trifluoromethyl)Phenyl)Propenamide is a specialized trifluoromethylated organic compound that serves as a high-value intermediate for advanced chemical synthesis. Its molecular architecture, featuring dual trifluoromethylphenyl groups and a cyano-hydroxy-propenamide backbone, makes it a critical building block for developing novel active ingredients. This compound is essential for research and development chemists in the pharmaceutical and agrochemical sectors seeking to incorporate fluorinated motifs to enhance the metabolic stability, bioavailability, and binding affinity of target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and oncology.
• Agrochemical Research: Used to develop advanced active ingredients for crop protection products, where the trifluoromethyl group improves lipophilicity and biological activity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique optical or electronic properties.
• Chemical Synthesis: A versatile building block for constructing complex molecules in medicinal chemistry and process development labs.
• Fluorine Chemistry Studies: Used in academic and industrial research to study the effects of fluorine substitution on molecular conformation and reactivity.

Basic Information

Product Name	Alpaha-Cyano-β-Hydroxy-n-(4-(Trifluoromethyl)Phenyl)-3-(4-(Trifluoromethyl)Phenyl)Propenamide
CAS No.	136185-95-0
Molecular Formula	C24H14F6N2O2
Molecular Weight	476.38 g/mol
Synonyms	α-Cyano-β-hydroxy-N-[4-(trifluoromethyl)phenyl]-3-[4-(trifluoromethyl)phenyl]propenamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide; 136185-95-0; (2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-3-[4-(trifluoromethyl)phenyl]prop-2-enamide; Propenamide, α-cyano-β-hydroxy-N-[4-(trifluoromethyl)phenyl]-3-[4-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our Alpaha-Cyano-β-Hydroxy-n-(4-(Trifluoromethyl)Phenyl)-3-(4-(Trifluoromethyl)Phenyl)Propenamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect this light-sensitive compound from degradation and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.