Description

Ethyl 2-{Benzyl[(tert-Butoxy)Carbonyl]Amino}Acetate is a high-purity, protected amino acid ester derivative widely used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring reliable, high-quality intermediates for complex molecule construction. It is particularly valuable for pharmaceutical development, peptide synthesis, and the production of fine chemicals where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing modified amino acid motifs.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains.
• Organic Building Block: Utilized in medicinal chemistry for the construction of novel chemical entities and combinatorial libraries during drug discovery.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific chiral centers or functional groups.
• Bioconjugation Chemistry: Acts as a reagent for introducing protected amine handles onto molecules for subsequent labeling or linker attachment.
• Academic & Industrial Research: Used in R&D laboratories for method development and exploring new synthetic pathways.

Basic Information

Product Name	Ethyl 2-{Benzyl[(tert-Butoxy)Carbonyl]Amino}Acetate
CAS No.	136159-62-1
Molecular Formula	C17H25NO4
Molecular Weight	307.39 g/mol
Synonyms	Ethyl N-[(benzyloxy)carbonyl]-N-(tert-butoxycarbonyl)glycinate; Ethyl N-Boc-N-Cbz-glycinate; N-Boc-N-Cbz-Glycine Ethyl Ester; Boc-Cbz-Gly-OEt; (tert-Butoxy)carbonyl(benzyl)aminoacetic Acid Ethyl Ester; Ethyl 2-[(N-Benzyloxycarbonyl-N-tert-butoxycarbonyl)amino]acetate; Glycine, N-[(benzyloxy)carbonyl]-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-{Benzyl[(tert-Butoxy)Carbonyl]Amino}Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.