Description

2-Ethynyl-Indan-2-Ol is a specialized organic compound featuring both an ethynyl and a hydroxyl functional group on a fused indane ring system. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds and complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Serves as a building block for creating novel pesticides and herbicides with specific activity profiles.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Acts as a precursor for organic electronic materials and polymers due to its conjugated ethynyl group.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the synthesis of complex natural product analogs.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	2-Ethynyl-Indan-2-Ol
CAS No.	136121-30-7
Molecular Formula	C₁₁H₁₀O
Molecular Weight	158.20 g/mol
Synonyms	2-Ethynyl-2-indanol; 2-Ethynylindan-2-ol; 2-Indanol, 2-ethynyl-; 1H-Inden-2-ol, 2-ethynyl-2,3-dihydro-; 2-(Ethynyl)-2,3-dihydro-1H-inden-2-ol; 2-Ethynyl-2,3-dihydro-1H-inden-2-ol; Building block 136121-30-7
EINECS	Contact for details

Quality Control

Every batch of 2-Ethynyl-Indan-2-Ol is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.