Description

Heat Shock Factor, Human CAS NO 136111-36-9 is a highly purified protein critical for regulating the cellular stress response. This factor is essential for research into protein folding, cellular protection mechanisms, and the molecular basis of various diseases. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in proteomics, drug discovery, and the development of therapeutic interventions for conditions related to proteostasis.

Application

• Biochemical Research: Used as a key reagent in studies of heat shock protein (HSP) gene expression and transcriptional regulation.
• Drug Discovery Screening: Serves as a target protein in high-throughput assays to identify novel modulators of the heat shock response pathway.
• Proteomics & Protein Interaction Studies: Employed in pull-down assays, co-immunoprecipitation, and mass spectrometry to map protein-protein interaction networks.
• Cell Stress & Apoptosis Research: Investigated for its role in cellular survival under thermal, oxidative, or chemical stress conditions.
• Therapeutic Development: Used in research focused on neurodegenerative diseases, cancer, and other disorders characterized by protein misfolding.
• In Vitro Diagnostic (IVD) Development: May be used as a component or calibrator in the development of research-use-only (RUO) diagnostic kits.

Basic Information

Product Name	Heat Shock Factor, Human
CAS No.	136111-36-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HSF, HSF1, Heat Shock Transcription Factor 1, Heat Shock Factor Protein 1, HSTF 1, Heat Shock Factor 1 (Human), HSF1 Protein, Recombinant Human HSF1, Heat Shock Factor (Human)
EINECS	Contact for details

Quality Control

Our Heat Shock Factor, Human is produced under stringent conditions to ensure high purity and biological activity. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, Western Blot, and functional activity assays. Certificates of Analysis (COA) detailing purity, concentration, and specific activity are provided to guarantee batch-to-batch consistency and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below in a non-frost-free freezer. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE/Western Blot)	Corresponds to Human HSF1
Purity (SDS-PAGE)	> 90%
Endotoxin Level (LAL)	< 1.0 EU/µg
Biological Activity	Confirmed by DNA-binding or reporter assay
Protein Concentration	As per COA
Formulation	Lyophilized from a buffer solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.