Description

Nhp2 Protein CAS NO 136111-26-7 is a high-purity, recombinant protein essential for research in RNA processing and ribonucleoprotein (RNP) complex assembly. This product is critical for scientists investigating the molecular mechanisms of pre-mRNA splicing and the biogenesis of small nucleolar ribonucleoproteins (snoRNPs). It is primarily utilized by researchers in academic institutions, pharmaceutical R&D, and biotechnology companies focused on genetic regulation, molecular biology, and the development of targeted therapeutics.

Application

• Biochemical Research: Used as a key component in in vitro studies of spliceosome and snoRNP assembly and function.
• Protein-Protein Interaction Studies: Employed in pull-down assays, co-immunoprecipitation, and yeast two-hybrid screens to map interaction networks.
• Enzymatic Activity Assays: Serves as a substrate or co-factor in enzymatic studies related to RNA modification and processing.
• Structural Biology: Provides a purified protein source for X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy.
• Antigen Production: Can be used to generate specific antibodies for immunological detection and localization studies.
• Cell-Free Systems: Incorporated into reconstituted systems to study the mechanics of RNA maturation pathways.

Basic Information

Item	Details
Product Name	Nhp2 Protein
CAS No.	136111-26-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	NHP2; NHP2 Ribonucleoprotein; NHP2 Homolog, H/ACA Ribonucleoprotein Subunit; NHP2 Protein (Yeast); NHP2-like Protein 1; NHP2L1; 15.5K Protein; snoRNP Protein NHP2; Non-Histone Protein 2
EINECS	Contact for details

Quality Control

Our Nhp2 Protein is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analysis, including purity assessment by SDS-PAGE and HPLC, confirmation of identity by mass spectrometry, and functional activity testing. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store lyophilized protein at -20°C or below. Reconstituted protein aliquots should be stored at -70°C to -80°C and avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (MS)	Conforms
Purity (SDS-PAGE)	≥ 95%
Purity (HPLC)	≥ 90%
Endotoxin Level	< 1.0 EU/µg
Biological Activity	Functionally active in binding assays
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.