Description

Dl-n-Boc-3-Pyrazol-1-Yl-Alanine CAS NO 136086-12-9 is a protected amino acid derivative featuring a pyrazole moiety, serving as a crucial chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates for the development of novel pharmaceuticals and bioactive compounds. It is primarily utilized in peptide chemistry and medicinal chemistry for constructing complex molecular architectures, making it vital for pharmaceutical R&D and fine chemical production.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptide-based drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the protected Dl-alanine derivative with a pyrazole functional group.
• Medicinal Chemistry: Serves as a versatile building block for creating compound libraries in drug discovery programs targeting various diseases.
• Bioconjugation: The reactive pyrazole group and protected amine make it suitable for creating labeled peptides or protein conjugates for biochemical studies.
• Agrochemical Research: Employed in the synthesis of novel compounds with potential herbicidal or pesticidal activity.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities and corporate research laboratories exploring new chemical entities.

Basic Information

Product Name	Dl-n-Boc-3-Pyrazol-1-Yl-Alanine
CAS No.	136086-12-9
Molecular Formula	C11H17N3O4
Molecular Weight	255.27 g/mol
Synonyms	DL-N-BOC-3-(1H-PYRAZOL-1-YL)ALANINE; Boc-DL-3-(1H-Pyrazol-1-yl)alanine; (RS)-2-[(tert-Butoxycarbonyl)amino]-3-(1H-pyrazol-1-yl)propanoic acid; 1H-Pyrazole-1-propanoic acid, α-[[(1,1-dimethylethoxy)carbonyl]amino]-, (α-RS)-; tert-Butyl (RS)-2-amino-3-(1H-pyrazol-1-yl)propanoate, N-Boc protected; DL-3-(Pyrazol-1-yl)alanine N-tert-Butoxycarbonyl derivative; N-Boc-DL-3-(1-Pyrazolyl)alanine; Boc-DL-Pra(3-Pyz)-OH
EINECS	Contact for details

Quality Control

Our Dl-n-Boc-3-Pyrazol-1-Yl-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with the standards expected for fine chemical and pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.