Description

(1S,2R,3R)-1,2,3,4-Tetrahydro-7-Hydroxy-1-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-2,3-Naphthalenedimethanol is a high-purity, stereochemically defined naphthalene derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chiral building block, enabling the development of novel active pharmaceutical ingredients (APIs) and complex natural product analogs. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating molecules with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Asymmetric Synthesis: Utilized as a complex, enantiomerically pure starting material or ligand scaffold for catalytic asymmetric transformations.
• Natural Product Synthesis: Acts as a core structural motif for the total synthesis of complex natural products containing tetralin or naphthalene frameworks.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme mechanisms and biological pathways.
• Agrochemical Research: Used in the discovery and development of new, stereospecific pesticides and herbicides.
• Material Science Research: Investigated as a monomer or dopant for creating advanced organic electronic materials with specific optical properties.

Basic Information

Product Name	(1S,2R,3R)-1,2,3,4-Tetrahydro-7-Hydroxy-1-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-2,3-Naphthalenedimethanol
CAS No.	136082-41-2
Molecular Formula	C21H26O7
Molecular Weight	390.43 g/mol
Synonyms	1,2,3,4-Tetrahydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-2,3-naphthalenedimethanol; (1S,2R,3R)-Tetrahydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-2,3-naphthalenedimethanol; NSC 339579; 2,3-Naphthalenedimethanol, 1,2,3,4-tetrahydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-, (1S,2R,3R)-; (1S,2R,3R)-1,2,3,4-Tetrahydro-7-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-6,8-dimethoxy-2,3-naphthalenedicarbinol
EINECS	Contact for details

Quality Control

Our production of (1S,2R,3R)-1,2,3,4-Tetrahydro-7-Hydroxy-1-(4-Hydroxy-3-Methoxyphenyl)-6,8-Dimethoxy-2,3-Naphthalenedimethanol adheres to stringent quality protocols suitable for research and development applications. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided to support your critical R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.