Description

7-(Bromomethyl)-2-Naphthonitrile is a versatile brominated naphthonitrile derivative that serves as a critical building block in advanced organic synthesis. Its reactive bromomethyl group adjacent to the electron-withdrawing nitrile functionality makes it a valuable precursor for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators, leveraging its naphthalene core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science: Building block for organic semiconductors, liquid crystals, and photoactive polymers due to its rigid, conjugated structure.
• Chemical Biology: Utilized in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	7-(Bromomethyl)-2-Naphthonitrile
CAS No.	135942-98-2
Molecular Formula	C12H8BrN
Molecular Weight	246.10 g/mol
Synonyms	2-Naphthonitrile, 7-(bromomethyl)-; 7-Bromomethyl-2-naphthonitrile; 2-Cyano-7-(bromomethyl)naphthalene; 7-(Bromomethyl)naphthalene-2-carbonitrile; (7-Bromomethyl-naphthalen-2-yl)-acetonitrile; 135942-98-2; 7-Bromomethyl-2-cyanonaphthalene
EINECS	Contact for details

Quality Control

Our 7-(Bromomethyl)-2-Naphthonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliable batch-to-batch consistency for your development and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and reactivity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.