Description

Bicyclo[2.2.2]Octane-1-Carboxylic Acid, 4-Amino-, Ethyl Ester is a high-purity, functionalized bicyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its rigid, three-dimensional bicyclo[2.2.2]octane scaffold and strategically positioned amino and ester functional groups make it invaluable for constructing complex molecular architectures with precise spatial control. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst design, and materials science.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Ligand and Catalyst Precursor: Used to synthesize specialized ligands for asymmetric catalysis and organometallic complexes.
• Agrochemical Research: Serves as a core structure for designing new herbicides and fungicides with unique modes of action.
• Advanced Material Synthesis: Employed in the creation of monomers for high-performance polymers, liquid crystals, and organic frameworks (MOFs/COFs).
• Chemical Biology Probe: Utilized to develop molecular probes and tags for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Bicyclo[2.2.2]Octane-1-Carboxylic Acid, 4-Amino-, Ethyl Ester
CAS No.	135908-45-1
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	4-Aminobicyclo[2.2.2]octane-1-carboxylic acid ethyl ester; Ethyl 4-aminobicyclo[2.2.2]octane-1-carboxylate; 1-Carbethoxy-4-aminobicyclo[2.2.2]octane; 4-Amino-BCO ethyl ester; Bicyclo[2.2.2]octan-1-carboxylic acid, 4-amino-, ethyl ester; 4-Aminobicyclo[2.2.2]octane-1-ethyl carboxylate; 1-Ethoxycarbonyl-4-aminobicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.2]Octane-1-Carboxylic Acid, 4-Amino-, Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, enantiomeric excess (if applicable), and impurity profiles. Our quality management system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.