Description

(S)-tert-Butyl 3-Oxo-1-Phenylpropylcarbamate CAS NO 135865-78-0 is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the production of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a precursor or auxiliary in stereoselective reactions to introduce the (S)-configuration into target molecules.
• Peptidomimetics Research: Serves as a protected β-amino acid derivative in the design and synthesis of novel peptide-like compounds for drug discovery.
• Agrochemical Development: Employed in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of chiral ligands used in homogeneous catalysis.
• Academic & Process Chemistry: Utilized in laboratory-scale research and process development for route scouting and optimization of synthetic pathways.

Basic Information

Product Name	(S)-tert-Butyl 3-Oxo-1-Phenylpropylcarbamate
CAS No.	135865-78-0
Molecular Formula	C14H19NO3
Molecular Weight	249.31 g/mol
Synonyms	(S)-3-Oxo-1-phenyl-1-[(tert-butoxycarbonyl)amino]propane; (S)-1-[(tert-Butoxycarbonyl)amino]-3-oxo-1-phenylpropane; (S)-Boc-3-oxo-1-phenylpropylamine; (S)-tert-Butyl (3-oxo-1-phenylpropyl)carbamate; (S)-N-Boc-3-oxo-1-phenylpropylamine; (S)-1-Phenyl-3-oxo-1-[(tert-butoxycarbonyl)amino]propane; (S)-β-Amino ketone Boc-protected derivative
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl 3-Oxo-1-Phenylpropylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.