Description

B15R Protein, Vaccinia Virus CAS NO 135847-82-4 is a recombinant protein derived from the vaccinia virus, a critical reagent in immunological and virological research. This protein is essential for studying viral pathogenesis, host immune evasion mechanisms, and for the development of novel vaccine platforms and therapeutic interventions. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in virology, immunology, and vaccine development.

Application

• Vaccine Research & Development: A key antigen and tool for studying immune responses in next-generation vaccine platforms, including viral vector-based vaccines.
• Virology Studies: Used to investigate the molecular biology, replication cycle, and pathogenesis of the vaccinia virus and related poxviruses.
• Immunoassay Development: Serves as a critical standard, calibrant, or coating antigen in the development of ELISA, Western blot, and other diagnostic assays.
• Host-Pathogen Interaction Research: Essential for elucidating mechanisms of viral immune evasion and protein-protein interactions with host cell factors.
• Therapeutic Antibody Screening: Used as a target antigen in high-throughput screening for neutralizing antibodies and therapeutic candidates.
• Biochemical Characterization: Employed in protein structure-function studies, kinetics, and interaction analyses using techniques like SPR (Surface Plasmon Resonance).

Basic Information

Product Name	B15R Protein, Vaccinia Virus
CAS No.	135847-82-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Vaccinia Virus B15R Protein; VACV B15R; Vaccinia Virus Complement Control Protein; VCP; Vaccinia Virus Secreted Complement Control Protein; B15R; Vaccinia Virus 35 kDa Protein; p35
EINECS	Contact for details

Quality Control

Our B15R Protein is produced under stringent conditions to ensure high purity, biological activity, and batch-to-batch consistency. Each lot undergoes comprehensive analytical testing, including SDS-PAGE, HPLC, and functional activity assays. A comprehensive Certificate of Analysis (COA) detailing purity, concentration, endotoxin levels, and biological activity is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store frozen at -20°C to -80°C. Avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder or clear solution
Purity (SDS-PAGE)	≥ 95%
Identification (Mass Spec)	Conforms
Protein Concentration	As per COA (typically 0.1-1.0 mg/mL)
Endotoxin Level	< 1.0 EU/µg (LAL test)
Biological Activity	Confirmed by functional assay (e.g., complement inhibition binding assay)
Buffer Composition	Specified on COA (e.g., PBS, Tris buffer)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.