Description

Hepatocyte Nuclear Factor 3Beta CAS NO 135845-92-0 is a high-purity biochemical reference standard and research compound. This product is critical for advancing studies in liver development, metabolism, and gene regulation. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on hepatology, metabolic disorders, and transcription factor biology.

Application

• Biomedical Research: Used as a key reagent in studies of hepatocyte differentiation, liver development, and metabolic pathway regulation.
• Drug Discovery & Development: Serves as a target or tool compound in screening assays for novel therapeutics targeting metabolic diseases, diabetes, and non-alcoholic fatty liver disease (NAFLD).
• Molecular Biology: Essential for in vitro and in vivo experiments investigating the role of the HNF3β (FOXA2) transcription factor in gene expression.
• Diagnostic Development: May be used in the development and calibration of diagnostic assays related to liver function and metabolic syndromes.
• Academic & Institutional Research: A fundamental material for grant-funded research in developmental biology, endocrinology, and genomics.

Basic Information

Product Name	Hepatocyte Nuclear Factor 3Beta
CAS No.	135845-92-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HNF3β; Forkhead Box Protein A2; FOXA2; Hepatocyte Nuclear Factor 3-Beta; Transcription Factor HNF-3β; TCF-3B; HNF3B Protein
EINECS	Contact for details

Quality Control

Our Hepatocyte Nuclear Factor 3Beta is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization. Certificates of Analysis (COA) detailing purity, identity, and biological activity are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Biological Activity	Assessed by functional assay
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in appropriate aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.