Description

Hepatocyte Nuclear Factor 3Gamma CAS NO 135845-91-9 is a high-purity biochemical reagent critical for advanced life science research. This compound serves as a key modulator in the study of hepatocyte differentiation, gene regulation, and metabolic pathways. It is essential for researchers and developers in the fields of molecular biology, pharmaceutical R&D, and metabolic disease modeling who require reliable, high-quality reagents for their critical work.

Application

• Molecular Biology Research: Used as a transcription factor in studies of liver-specific gene expression and hepatocyte development.
• Pharmaceutical Development: A vital tool for screening and validating drug candidates targeting hepatic functions and metabolic disorders.
• Stem Cell Research: Employed in protocols for the differentiation of stem cells into hepatocyte-like cells for regenerative medicine applications.
• Toxicology Studies: Serves as a biomarker and functional agent in assessing hepatotoxicity and liver metabolism of new chemical entities.
• Gene Regulation Analysis: Utilized in chromatin immunoprecipitation (ChIP) assays and reporter gene studies to investigate transcriptional networks.
• Metabolic Disease Modeling: Critical for creating in vitro models of diseases such as non-alcoholic fatty liver disease (NAFLD) and diabetes.
• Biochemical Assay Standard: Acts as a reference standard in quantitative assays measuring hepatocyte nuclear factor activity.
• Academic & Institutional Research: Supports fundamental research in developmental biology and organogenesis at universities and research institutes.

Basic Information

Product Name	Hepatocyte Nuclear Factor 3Gamma
CAS No.	135845-91-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	HNF-3γ; Hepatocyte Nuclear Factor 3 Gamma; Forkhead Box A3; FOXA3; Transcription Factor HNF-3γ; HNF3G; TCF-3G; Hepatic Nuclear Factor 3-Gamma
EINECS	Contact for details

Quality Control

Our Hepatocyte Nuclear Factor 3Gamma is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes rigorous analytical testing, including purity verification by HPLC and functional activity assays. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and biological activity is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider aliquoting to minimize freeze-thaw cycles and maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Biological Activity	Assayed (Contact for details)
Endotoxin Level	< 1.0 EU/μg
Solubility	Soluble in appropriate buffers (e.g., PBS with DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.