Description

Cancer-Associated Retinopathy Antigen is a highly purified, biologically relevant protein used in advanced biomedical research and diagnostic development. This antigen is critical for studying autoimmune retinopathies and developing specific immunoassays to detect associated autoantibodies. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical companies focused on ophthalmic and neurological disorders.

Application

• Research Reagent: Used as a key antigen in immunological studies of Cancer-Associated Retinopathy (CAR) and other paraneoplastic syndromes.
• Diagnostic Development: Serves as the capture or detection antigen in the development of enzyme-linked immunosorbent assays (ELISA), Western blot, and other immunoassays for autoantibody detection.
• Biomarker Validation: Employed in clinical research to validate the presence and specificity of anti-retinal antibodies in patient serum samples.
• Therapeutic Target Research: Facilitates research into potential therapeutic interventions for autoimmune-mediated vision loss.
• Quality Control Standard: Acts as a reference standard for the calibration and quality control of diagnostic tests in commercial and clinical laboratory settings.
• Antibody Production: Used for immunizing animals to generate polyclonal or monoclonal antibodies specific to the retinopathy antigen.

Basic Information

Product Name	Cancer-Associated Retinopathy Antigen
CAS No.	135844-11-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	CAR Antigen; Recoverin; Cancer-Associated Retinopathy Protein; Neuronal Calcium Sensor Protein; Retinal Recoverin; Autoantigen in CAR; Neuronal Calcium-Binding Protein; Visinin-Like Protein 1 (VILIP-1)
EINECS	Contact for details

Quality Control

Our Cancer-Associated Retinopathy Antigen is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and biological activity. Each lot is characterized for identity and purity using advanced analytical techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and functional activity is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (SDS-PAGE / Immunoblot)	Conforms to standard
Purity (SDS-PAGE)	≥ 95%
Protein Content (BCA)	≥ 90%
Biological Activity (ELISA Binding)	Positive reactivity with reference antisera
Endotoxin Level (LAL)	< 1.0 EU/μg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.