Description

Argipressin, Beta Mercapto Beta,β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Lys-(N(Epsilon)-Biotinamidocaproate)Nh2(9)- is a sophisticated, biotinylated analog of the neurohypophysial hormone arginine vasopressin. This modified peptide is engineered for advanced research applications, offering a powerful tool for studying vasopressin receptor interactions and signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic biochemists, and contract research organizations (CROs) focused on endocrinology, neuroscience, and targeted drug delivery systems.

Application

• Biochemical Research: As a high-affinity ligand for studying vasopressin V1a and V2 receptor binding kinetics, specificity, and downstream cellular effects.
• Affinity Purification & Pull-Down Assays: The biotin tag enables efficient immobilization on streptavidin-coated surfaces for isolating receptor complexes or associated proteins.
• Signal Transduction Studies: Investigation of G-protein coupled receptor (GPCR) activation, second messenger systems (e.g., cAMP, calcium mobilization), and cellular responses in model systems.
• Diagnostic Development: Potential use as a critical component in the development of competitive immunoassays or biosensors for vasopressin pathway analysis.
• Drug Discovery & Lead Optimization: Serving as a reference compound or a starting point for the design of novel vasopressin receptor agonists or antagonists with modified pharmacokinetic profiles.
• Cellular Imaging & Localization: Conjugation with fluorescent probes via the biotin handle for visualizing receptor distribution and internalization using microscopy techniques.

Basic Information

Item	Detail
Product Name	Argipressin, Beta Mercapto Beta,β-Cyclopentamethylenepropionic Acid(1)-o-Methyl-Tyr(2)-Lys-(N(Epsilon)-Biotinamidocaproate)Nh2(9)-
CAS No.	135484-50-3
Molecular Formula	C66H103N17O16S2
Molecular Weight	1394.8 g/mol
Synonyms	[Mpa1, o-Me-Tyr2, Lys8(biotinamidocaproate)]-Vasopressin; Biotinylated Argipressin Analog; Biotin-LC-[Mpa1, o-Me-Tyr2, Arg8]-Vasopressin; Biotinamidocaproyl-Lys8-Argipressin; Biotinylated Vasopressin Peptide; Biotin-AVP analog; Research Peptide 135484-50-3; Biotin-LC-[1-β-mercapto-β,β-cyclopentamethylenepropionic acid, 2-O-methyltyrosine, 8-lysine(biotinamidocaproate)]-vasopressin
EINECS	Contact for details

Quality Control

Our Argipressin analog is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for critical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to GMP-like guidelines for peptide synthesis and purification, ensuring the product meets the exacting standards required for pharmaceutical and life science research. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Mass spectrum consistent with theoretical molecular weight
Purity (HPLC)	≥ 95%
Assay (HPLC)	≥ 97% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.