Description

Strontiumranelate CAS NO 135459-90-4 is a synthetic organic strontium salt specifically developed for its role in bone metabolism. This compound is of significant interest in the pharmaceutical and advanced research sectors due to its targeted biological activity. It is primarily utilized by manufacturers in the pharmaceutical industry for the development of treatments related to bone health, as well as by research institutions conducting metabolic and orthopedic studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription medications for osteoporosis and other bone disorders.
• Clinical Research & Development: Serves as a key reference standard and investigational material in preclinical and clinical trials for bone-targeting therapies.
• Biochemical Research: Used in laboratory studies to investigate cellular signaling pathways related to osteoblast and osteoclast activity.
• Analytical Reference Standard: Employed in quality control laboratories for method development, validation, and assay calibration in pharmaceutical analysis.
• Advanced Material Synthesis: Potential precursor or additive in the development of novel biomaterials for bone graft substitutes and implants.

Basic Information

Product Name	Strontiumranelate
CAS No.	135459-90-4
Molecular Formula	C12H6N2O8SSr2
Molecular Weight	513.49 g/mol
Synonyms	Strontium Ranelate; Distrontium 5-[bis(2-oxido-2-oxoethyl)amino]-4-cyano-3-(carboxymethyl)thiophene-2-carboxylate; Protelos; Protos; Osseor; BGP-12A; S12911; Distrontium ranelate; Strontium ranelate hydrate
EINECS	Contact for details

Quality Control

Our Strontiumranelate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and reference standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.