Description

Tendamistat (12-26) CAS NO 135307-06-1 is a defined peptide fragment derived from the full-length Tendamistat protein. This specific sequence is of significant interest in biochemical and pharmaceutical research for its role in studying protein-protein interactions and enzyme inhibition mechanisms. It serves as a critical tool for researchers in structural biology and drug discovery. This high-purity peptide is essential for academic institutions, biotech R&D departments, and pharmaceutical companies developing novel therapeutic approaches.

Application

• Biochemical Research: Used as a reference standard and active component in studies of α-amylase inhibition mechanisms.
• Pharmaceutical Development: Serves as a key intermediate or model compound in the design and screening of new therapeutic agents targeting carbohydrate metabolism.
• Structural Biology: Employed in X-ray crystallography and NMR spectroscopy to elucidate three-dimensional protein structures and binding sites.
• Enzyme Kinetics: Utilized in assays to determine inhibition constants (Ki) and study the kinetics of enzyme-inhibitor interactions.
• Peptide Chemistry Studies: Acts as a substrate or model peptide in methodological development for synthesis, purification, and analysis.
• Academic & Educational Use: Provides a well-characterized peptide for graduate-level research and advanced laboratory coursework in biochemistry.

Basic Information

Product Name	Tendamistat (12-26)
CAS No.	135307-06-1
Molecular Formula	C69H111N21O22S2
Molecular Weight	1634.9 g/mol
Synonyms	Tendamistat fragment 12-26; H-Tyr-Cys-Asn-Thr-Pro-Gly-Tyr-Thr-Cys-Gly-Ile-Val-Asn-Arg-Phe-OH; TENDAMISTAT (12-26) PEPTIDE; α-amylase inhibitor tendamistat (12-26); HOE 467 A (12-26); Tendamistat peptide (12-26); TMD (12-26)
EINECS	Contact for details

Quality Control

Every batch of Tendamistat (12-26) is produced and analyzed under strict quality management protocols. We ensure compliance with high-purity standards suitable for research applications. Identity, purity, and composition are verified through multiple orthogonal analytical techniques, including HPLC and MS. A comprehensive Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with each shipment to guarantee traceability and consistency for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.