Description

Sulfonyl Amide, Polymer-Supported is a functionalized resin designed for use as a versatile reagent and scavenger in solid-phase organic synthesis (SPOS). This product is engineered to provide a robust and recoverable platform for chemical transformations, offering significant advantages in process simplification and purification. It is a critical tool for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries, enabling efficient parallel synthesis and library generation.

Application

• Solid-phase synthesis of sulfonamides and related compounds.
• Scavenging agent for excess electrophiles (e.g., sulfonyl chlorides, acid chlorides) in solution-phase reactions.
• Reusable catalyst or reagent support for combinatorial chemistry and high-throughput screening.
• Facilitates the purification of reaction mixtures by filtration, eliminating tedious liquid-liquid extraction or chromatography.
• Development of polymer-supported reagents for flow chemistry applications.
• Research tool in medicinal chemistry for the rapid generation and screening of compound libraries.

Basic Information

Item	Detail
Product Name	Sulfonyl Amide, Polymer-Supported
CAS No.	135266-23-8
Molecular Formula	Polymer-supported (Contact for details)
Molecular Weight	Polymer-supported (Contact for details)
Synonyms	Polymer-Bound Sulfonyl Amide; Polystyrene-Supported Sulfonamide; Solid-Supported Sulfonamide; PS-Sulfonamide; Sulfonamide Resin; Wang Sulfonamide Resin (type); Merrifield Sulfonamide Resin (type); 4-Sulfamoylbenzyl Alcohol Polymer-Bound
EINECS	Contact for details

Quality Control

Our Sulfonyl Amide, Polymer-Supported products undergo rigorous quality testing to ensure batch-to-batch consistency and performance in synthetic applications. Key parameters such as loading capacity, functional group integrity, and bead morphology are strictly controlled. A Certificate of Analysis (COA) detailing lot-specific results is available upon request, supporting compliance with internal quality standards for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The resin is moisture-sensitive (hygroscopic); ensure the container is sealed after use to prevent exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to beige beads
Loading Capacity	0.5 - 2.0 mmol/g (typical, grade dependent)
Mesh Size	100-200 mesh (or as specified)
Functional Group	Sulfonyl Amide (-SO2NH2)
Matrix	Polystyrene cross-linked with divinylbenzene (1-2% DVB)
Swelling Volume	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.