Description

5-Amino-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carbonitrile is a high-purity, heterocyclic organic compound featuring a pyrazole core substituted with an amino group, a fluorinated phenyl ring, and a nitrile functionality. This unique structure makes it a critical building block (advanced intermediate) for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a versatile scaffold for developing new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Synthesis Building Block: Used in organic synthesis to construct more complex heterocyclic systems due to its reactive amino and nitrile groups.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	5-Amino-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carbonitrile
CAS No.	135108-48-4
Molecular Formula	C10H7FN4
Molecular Weight	202.19 g/mol
Synonyms	5-Amino-1-(2-fluorophenyl)-1H-pyrazole-4-carbonitrile; 1-(2-Fluorophenyl)-5-amino-1H-pyrazole-4-carbonitrile; 5-Amino-1-(2-fluorophenyl)-4-cyanopyrazole; 4-Cyano-5-amino-1-(2-fluorophenyl)pyrazole; 135108-48-4; 2-Fluorophenyl-5-amino-pyrazole-4-carbonitrile; 5-Amino-1-(o-fluorophenyl)-1H-pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Amino-1-(2-Fluorophenyl)-1H-Pyrazole-4-Carbonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.