Description

Adenosine-5-N'-(2,4-Dinitro-5-Fluorophenyl)Phosphohydrazine is a specialized nucleotide derivative designed for advanced biochemical research and synthesis. This compound serves as a critical building block and reagent in the development of novel pharmaceuticals and diagnostic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the synthesis of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving kinases and polymerases.
• Probe Development: Acts as a core structure for developing fluorescent or affinity probes to study nucleic acid-protein interactions.
• Diagnostic Reagent Synthesis: Employed in the creation of specialized reagents for molecular diagnostics and assay development.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and nucleotide metabolism.

Basic Information

Product Name	Adenosine-5-N'-(2,4-Dinitro-5-Fluorophenyl)Phosphohydrazine
CAS No.	135101-78-9
Molecular Formula	C16H16FN9O8P
Molecular Weight	521.33 g/mol
Synonyms	5'-O-[N-(2,4-Dinitro-5-fluorophenyl)phosphoramidoyl]adenosine; Adenosine 5'-[N-(2,4-dinitro-5-fluorophenyl)phosphoramidate]; DNPF-Adenosine Phosphoramidate; 2',3'-O-Isopropylideneadenosine 5'-[N-(2,4-dinitro-5-fluorophenyl)phosphoramidate] (protected form); FDNP-Adenosine derivative; Nucleoside phosphoramidate reagent
EINECS	Contact for details

Quality Control

Our Adenosine-5-N'-(2,4-Dinitro-5-Fluorophenyl)Phosphohydrazine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Custom synthesis and purity grades are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed under an inert atmosphere if specified and opened only in a controlled, dry environment.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.